題目: Construction of lncRNA?miRNA?mRNA networks reveals functional lncRNAs in abdominal aortic aneurysm
DOI: 10.3892/etm.2018.6690
數(shù)據(jù)集: GSE47472, GSE57691
樣本:
GSE7084 & Yang et al: 人mRNA
Yang et al: lncRNA
GSE24194: 兔miRNA
分析方法:
DEG: R語言(corrected P-value of <0.05 and |log2 fold?change (FC)|≥1)
DAVID: GO和KEGG富集分析
StarBase: 構(gòu)建lncRNA?miRNA pairs
miRcode, StarBase, Targetscan: 構(gòu)建miRNA?mRNA pairs
補充: only downregulated miRNAs and upregulated mRNAs were integrated into the ceRNA network for upregulated lncRNAs
only upregulated miRNAs and downregulated mRNAs were integrated into the ceRNA network fir downregulated lncRNAs
文章數(shù)據(jù):
1.各個數(shù)據(jù)集的DEG熱圖
2.GO和KEGG富集結(jié)果
3.上調(diào)lncRNAs的網(wǎng)絡(luò)
4.下調(diào)lncRNAs的網(wǎng)絡(luò)
5.關(guān)鍵lncRNA?mRNA?biological processes subnetwork
