A 56-year-old man presents to his physician complaining of severe fatigue. He began to feel increasingly tired about 6 months ago, but believes that his fatigue has been worsening over the past 3 weeks. He also notes that he has had a nonproductive cough for about 2 weeks,and has experienced several episodes of drenching night sweats. On examination, he has several large bruises on his extremities but recalls no injuries. Abdominal examination reveals massive enlargement of both the liver and the spleen, without any lymphadenopathy.Laboratory tests show:WBC count 12,000/mm3, Neutrophils 58%, Eosinophils 7%, Lymphocytes 30%, Monocytes 0%, Basophils 5%, RBC count 3.0/mm3, Hemoglobin 7.5 mg/dL, Platelet count 18,000/mm3, Peripheral blood smear reveals irregular nuclei and cell membranes, as well as cytoplasmic projections.
Questions:
What is the patient's most likely diagnosis?
What is the treatment to the disease?
本次病例中:一名56歲的男性患者向醫(yī)生主訴自覺(jué)重度疲乏笼吟,而且疲乏已持續(xù)6個(gè)月,自覺(jué)加重3周劣纲〔昕患者主訴在無(wú)誘因下出現(xiàn)長(zhǎng)達(dá)2周的咳嗽像街,并且經(jīng)常被夜汗徹底濕透。體檢中,患者四肢存在散在的大面積淤青立倍,但是患者并未有外傷史。腹部觸診發(fā)現(xiàn)患者肝臟和脾臟非常巨大侣滩,但未能發(fā)現(xiàn)淋巴結(jié)腫塊口注。
實(shí)驗(yàn)室檢查結(jié)果如下:白細(xì)胞 12,000/mm3,中性粒細(xì)胞 58%君珠,嗜酸性粒細(xì)胞 7%寝志,淋巴細(xì)胞 30%,單核細(xì)胞 0%策添,嗜堿性粒細(xì)胞 5%材部,紅細(xì)胞 3.0/mm3,血紅蛋白 7.5 mg/dL唯竹,血小板 18,000/mm3乐导,血液涂片鏡檢中發(fā)現(xiàn)患者細(xì)胞核和細(xì)胞膜呈不規(guī)則狀,胞漿周邊不規(guī)則突起樣浸颓。
問(wèn)題:
1物臂、患者最可能的診斷是什么?
2猾愿、對(duì)于該疾病的治療方式有哪些鹦聪?