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They may sound like weapons for Ant-Man’s next nemesis, but the microscopic lasers could greatly improve biologists’ ability to
track the movement of individual cells—a possible boon to fields ranging from developmental biology to cancer research.
這篇文章主要是講制造細胞大小的激光器患整。它的優(yōu)勢是非常明顯的玩裙,可以比fluorescence和radio frequency ID更好。
不過要制造一臺激光器泉蝌,就需要有兩個條件:
- 能夠受到激發(fā)而產(chǎn)生光的材料蚜厉,一般是指晶體
- 一個共振腔
難點在于如何在細胞里裝進一個容器
以下嘗試:
- In culture, they mixed cells with tiny plastic spheres 5 to 10 micrometers in diameter that had been “doped” with a fluorescent dye. The beads served as the cavities, the dye as the medium.
- get cells to take up plastic beads, and they created two other kinds of resonating spheres as well
那這么做的目的在于什么呢事富?
- 追蹤細胞的運動,每一個細胞的塑料球都是有一點不同旋恼,這樣他們的激發(fā)出來的激光就會有一點波長上的區(qū)別吏口。這樣就可以分開每個細胞了。
- 每種tissue會吸收不同的beads冰更,那么相比于fluorescence产徊,則有著更大的優(yōu)勢∈裣福可以定位millions of cells
難點舟铜,更小的beads,更好的吸收奠衔。