對于fragment counts建模可改善單細(xì)胞 ATAC-seq 分析(而非read counts/binary counts): https://www.nature.com/articles/s41592-023-02112-6 提出了改進(jìn)scATAC-seq counts matrix的PIC方法崇决,能夠提供對scATAC-seq更準(zhǔn)確的定量矩陣材诽,并改進(jìn)下游分析 https://www.nature.com/articles/s41592-023-02103-7 方法鏈接:https://github.com/Zhen-Miao/PICsnATAC