差異的甲基化
差異的甲基化位點(diǎn)位于基因的prometer區(qū)域，我們才去保留，主要包括（TSS200和TSS1500）
注釋文件來自ChAMP工具包幻工，data一下即可
一般的差異定義標(biāo)準(zhǔn)為
image.png
參考文獻(xiàn)：Immune Signature-Based Subtypes of Cervical Squamous Cell Carcinoma Tightly Associated with
Human Papillomavirus Type 16 Expression, Molecular Features, and Clinical Outcome
差異標(biāo)準(zhǔn)提高：
image.png
參考文獻(xiàn)：Epigenetic age acceleration of cervical squamous cell carcinoma converged to human papillomavirus 16/18 expression, immunoactivation, and favourable prognosis
promoter regions 默認(rèn)（TSS200和TSS1500）
image.png
image.png
參考文獻(xiàn)：The signature of HBV-related liver disease in peripheral blood mononuclear cell DNA methylation
image.png
image.png
image.png
