1. 健康、未孕女性子宮中存在微生物群落
多年來弄贿,有報道稱未孕女性子宮中存在活菌春锋。盡管許多研究采取了預(yù)防措施以避免污染,但此類發(fā)現(xiàn)常常被認(rèn)為是宮頸和(/或)陰道菌群對樣本的污染差凹。培養(yǎng)的微生物與陰道和宮頸中發(fā)現(xiàn)的微生物相似期奔,包括乳酸桿菌、陰道加德納菌危尿、α-溶血性鏈球菌呐萌、鏈球菌、無乳鏈球菌谊娇、金黃色葡萄球菌肺孤、擬桿菌屬、GPAC济欢、腸球菌屬赠堵、大腸桿菌、念球菌屬法褥。最近茫叭,一些與非培養(yǎng)的研究發(fā)現(xiàn),大部分未懷孕女性子宮中存在微生物DNA半等。這種DNA可能來自子宮防御系統(tǒng)已成功處理的死亡微生物揍愁,也可能代表采樣期間陰道或?qū)m頸的污染。結(jié)合子宮內(nèi)活菌的檢測酱鸭,強有力的證據(jù)表明吗垮,微生物確實在健康、未孕女性的子宮內(nèi)定居凹髓。在其中一項研究的樣本中都發(fā)現(xiàn)了大量擬桿菌屬烁登,這些微生物在菌群中占比很大。菌群種類多樣,其他主要成員包括乳酸桿菌和埃希氏-志賀氏菌屬饵沧。
其他研究發(fā)現(xiàn)锨络,在子宮菌群中,乳酸桿菌而非擬桿菌是優(yōu)勢菌屬狼牺。然而羡儿,相關(guān)研究不多,參與研究的人數(shù)也不多是钥,因此很難就子宮菌群的組成得出任何一般性結(jié)論掠归。
2. 懷孕女性子宮中是否存在微生物仍然存在爭議
許多研究指出在足月妊娠的羊水、胎膜或胎盤中存在少量微生物悄泥。然而虏冻,其他研究未能支持這些發(fā)現(xiàn)。已檢測到的微生物包括微小脲原體弹囚、卷曲乳桿菌厨相、梭桿菌屬、泛菌屬鸥鹉、直腸真桿菌蛮穿、人型支原體、大腸桿菌毁渗、譚氏普雷沃氏菌践磅、多糖奈瑟菌和乳酸奈瑟菌。檢測到的微生物可能是來自FRS其他區(qū)域或身體其他部位的污染菌祝蝠。此外音诈,大多數(shù)研究指出微生物存在的研究都是基于對微生物DNA的檢測幻碱,而不是活菌绎狭,這些DNA可能來自被人體防御系統(tǒng)殺死的微生物。
女性生殖系統(tǒng)菌群系列
【女性生殖系統(tǒng)菌群之一】女性生殖系統(tǒng)結(jié)構(gòu)褥傍、生理與內(nèi)環(huán)境
【女性生殖系統(tǒng)菌群之二】生殖系統(tǒng)菌群受年齡和系統(tǒng)生理學(xué)變化的影響
【女性生殖系統(tǒng)菌群之二】女性性成熟時期生殖系統(tǒng)菌群
【女性生殖系統(tǒng)菌群之二】陰道菌群群落狀態(tài)及類型
【女性生殖系統(tǒng)菌群之二】影響陰道菌群和群落特征的因素
【女性生殖系統(tǒng)菌群之二】陰道真菌儡嘶、病毒以及宮頸菌群
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