1. TINs in the mammary TME demonstrate potent immunosuppression 2. scRNA-seq reveals di...
1. TINs in the mammary TME demonstrate potent immunosuppression 2. scRNA-seq reveals di...
1. PGAM5 deletion leads to accelerated cell senescence 為了明確小鼠aging和線粒體融合/分裂之間的關(guān)系,作者首先構(gòu)建...
1. ScRNA-seq identified 11 major cell types in mice abdominal aortic tissues Fig 1a: NA...
1. Itaconate activates Nrf2 在LPS-treated human macrophages中脾拆,衣康酸的豐度顯著升高 (a)瘸右,小鼠BMDM在LPS刺激...
免疫代謝[http://www.reibang.com/p/0ccc0d793fe2] 糖酵解,磷酸戊糖途徑和三羧酸循環(huán)[http://www.reibang.com/p...
1. DNA甲基化 1.1 基本概念 DNA甲基化是表觀遺傳修飾的主要方式垢袱,能在不改變DNA序列的前提下,改變遺傳表現(xiàn)墓拜。為外遺傳編碼(epigenetic code)的一部分...
癌癥液體活檢,是近年來炙手可熱的研究領(lǐng)域惶桐。其中最受人關(guān)注的是血液中的游離DNA(cfDNA)和循環(huán)腫瘤DNA(ctDNA)撮弧,因?yàn)橐呀?jīng)有大量的研究證實(shí),腫瘤在發(fā)生發(fā)展過程中會往...
宮頸癌是女性癌癥死亡的第四大原因姚糊,其中宮頸鱗狀細(xì)胞癌(CSCC)是最常見的類型贿衍。不幸的是,晚期救恨、轉(zhuǎn)移性或復(fù)發(fā)性CSCC的5年生存率僅為16.5%贸辈。盡管免疫檢查點(diǎn)阻斷(ICB)...
Evolutionary conservation analysis of human arachidonic acid metabolism pathway genes 1...
1. INO80 Correlates With Heart Development and HF 為了探究INO80 complex在心臟中的作用,作者首先檢測了它在心臟成...
文獻(xiàn)學(xué)習(xí)107-IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer1. Identification of IL-1β+ TAMs in PDAC Fig 1a-c: 作者對新鮮分離的來自naive 或 chemotherapy treat...
1. Identification of IL-1β+ TAMs in PDAC Fig 1a-c: 作者對新鮮分離的來自naive 或 chemotherapy treat...
1. Single-cell RNA sequencing analysis identifies synthetic smooth muscle cells as an e...
膿毒癥導(dǎo)致新生兒死亡的高風(fēng)險(xiǎn)被認(rèn)為是先天性免疫細(xì)胞反應(yīng)受損的結(jié)果肠槽;然而擎淤,臨床觀察到的新生兒膿毒癥高炎癥狀態(tài)與這一概念相矛盾。作者使用轉(zhuǎn)錄組秸仙、表觀遺傳學(xué)和免疫學(xué)方法證明大量的圍...
R語言繪圖包系列: R語言繪圖包01--優(yōu)秀的拼圖包patchwork[http://www.reibang.com/p/e57555d48c91] R語言繪圖包02--熱...
1. Myocardial infarction activates IRF3-dependent signaling We hypothesized that the hi...
1. LPS-Stimulated THP-1 Monocytic Cells Release Proinflammatory Microvesicles Enriched ...